The influence of the time elapsed from the intravenous pancreatic injection into a diabetic animal.The effect of the pancreatic extract injected into a diabetic animal by way of the blood.After a gap during World War I, he resumed his research and succeeded in isolating the antidiabetic pancreatic hormone (pancreine).įrom April 24 to June 23, 1921, Paulescu published four papers at the Romanian Section of the Society of Biology in Paris: Paulescu’s discovery of insulinIn 1916, he succeeded in developing an aqueous pancreatic extract which, when injected into a diabetic dog, proved to have a normalizing effect on blood sugar levels. In 1900, Paulescu returned to Romania, where he remained until his death (1931) as Head of the Physiology Department of the University of Bucharest Medical School, as well as a Professor of Clinical Medicine at the St. In 1897 he graduated with a Doctor of Medicine degree, and was immediately appointed as assistant surgeon at the Notre-Dame du Perpétuel-Secours Hospital. In the autumn of 1888, Paulescu left for Paris, where he enrolled in medical school. He graduated from the Mihai Viteazu High School in Bucharest, in 1888. He also had a particular gift for drawing and music and special inclinations towards natural sciences, such as physics and chemistry. He learned French, Latin and Ancient Greek at an early age, so that a few years later he became fluent in all these languages and was able to read classical works of Latin and Greek literature in the original. He displayed remarkable abilities as early as his first school years. Born in Bucharest, he was the first of four children of father Costache Paulescu and mother Maria Paulescu.
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